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The  22-250 Remington began
as a wildcat by necking down the 250-3000 Savage (also called the 250 Savage) to .22" caliber, by Harvey Donaldson in 1934.
The 250 Savage was designed by Charles Newton in 1915 and
named it the  250-3000 because it was a 25 (250) caliber, and would go 3,000 Feet per Second.
Somehow Remington got the rights to the design and started production under the 22-250 Remington label. 
I personally load and shoot this caliber and it is a great cartridge and easily produces 4,000 + Feet per Second velocities with 50 grain projectiles.
It is one of the best all round varmint cartridges and has outstanding accuracy.
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$ 1.95 per
Cartridge
22-250 Remington
22 Varminter
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